Senior / Principal Scientist, Medicinal Chemistry

Core responsibilities:

• Design and deliver medicinal chemistry strategy on project(s)
• Optimize small molecules through analysis of biochemical, biological, and ADME assay data
• Manage chemistry CROs for timely delivery of synthetic efforts
• Collaborate with cross-functional teams and machine learning team for project needs in high-paced data-driven environment

This role contributes to creating breakthrough technologies that transform health care by developing small molecules that edit protein structure and function to unlock presently undruggable targets and therapeutic modalities.

Required qualifications:

• PhD in synthetic organic or medicinal chemistry with at least 5 years' drug discovery experience in pharmaceutical industry OR BS/BA in chemistry with at least 10 years' experience
• Strong modern synthetic background with knowledge of state-of-the-art organic chemistry methodologies
• Experience managing external chemistry CROs
• Experience collaborating with machine learning teams preferred
• Strong communication and interpersonal skills

Compensation and benefits:

• Salary range: $126,000 - $214,500
• Healthcare coverage
• Annual incentive program
• Retirement benefits
• Broad range of other benefits

Flagship Pioneering invents and builds platform companies that transform human health, sustainability and beyond, creating breakthrough technologies to address humanity's most urgent challenges including curing intractable diseases and improving human health.