Senior Director, CMC Development, Biologics

• Own end-to-end CMC strategy and execution, including governance, integrated plans, scenario planning, supply forecasting, and risk management to deliver program and company milestones.
• Lead external CDMO strategy and oversight for drug substance and drug product, ensuring execution success through scope setting, operating cadence, and issue resolution.
• Provide technical leadership across upstream/downstream, analytical, formulation, fill/finish, and stability, guiding fit-for-stage development decisions and tech transfer readiness.
• Drive CMC regulatory deliverables and executive-level communication of status, decisions, risks, and mitigation plans while building high-performing internal and matrixed teams.

This role creates positive change by developing biological therapeutics that transform patient lives and address humanity's urgent health challenges, including curing intractable diseases and improving human health.

• Advanced degree (PhD preferred; MS with significant experience considered) in Chemical Engineering, Biochemistry, Pharmaceutical Sciences, or related discipline.
• 15+ years of biologics CMC experience spanning development through GMP manufacturing and external manufacturing oversight (drug substance and/or drug product).
• Proven ability to define CMC strategy and translate it into cross-functional deliverables, integrated plans, timelines, and budgets with strong program leadership.
• Demonstrated success managing external collaborations/CDMOs to deliver CMC development and manufacturing outcomes in fast-paced, matrixed environments.

The salary range for this role is $213,000 - $280,500. Metaphore Biotechnologies, Inc. currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits.