Global Health Full-time

Pioneering Medicines: Medical Director / Senior Medical Director, Clinical Development Lead

Flagship Pioneering

Posted

Feb 14, 2026

Location

USA

Type

Full-time

Compensation

$205000 - $335000

Mission

What you will drive

  • Lead the design of early clinical development plans (through human proof-of-concept) for Pioneering Medicines programs, in alignment with the Target Product Profile
  • Collaborate closely with senior clinical leaders, Project Leaders, Research, Strategy, and external advisors to define and refine clinical hypotheses and development strategies
  • Integrate clinical plans with translational, nonclinical, and regulatory development strategies to enable seamless progression from exploratory studies to first-in-human trials
  • Support program operations, resource planning, and interactions with internal governance and external partners

Impact

The difference you'll make

This role creates positive change by translating cutting-edge science from the Flagship Pioneering ecosystem into innovative medicines through rigorous development planning, ultimately creating life-changing treatments for patients with serious diseases and unmet medical needs.

Profile

What makes you a great fit

  • Physician Scientist: MD or MD with PhD with a robust scientific background
  • 3+ years or more of post-graduate/post-residency experience in industry or academic clinical research
  • Medical residency and/or subspecialty fellowship training highly preferred
  • Strong understanding of early clinical development and translational medicine, mechanisms of disease, and patient care paradigms in relevant therapeutic areas (oncology, immunology and/or metabolic diseases preferred)

Benefits

What's in it for you

The salary range for this role is $205,000 - $335,000. Pioneering Medicines currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits.

About

Inside Flagship Pioneering

Flagship Pioneering conceives, creates, resources, and develops first-in-category life science platform companies to transform human health and sustainability. Pioneering Medicines is an initiative of Flagship Pioneering focused on building a world-class biopharmaceutical R&D capability to develop life-changing treatments for patients.