Application Guide

How to Apply for Executive Director- 30 hrs/week

at AXYS

🏢 About AXYS

AXYS is a unique nonprofit dedicated specifically to supporting individuals with X and Y chromosome variations (such as Klinefelter syndrome, Turner syndrome, and others), making it a highly specialized advocacy organization. Working here offers the opportunity to directly impact a specific medical community through advocacy, research collaboration, and community building in a remote, flexible environment.

About This Role

As Executive Director at AXYS, you'll lead all aspects of this nonprofit's operations while working 30 hours weekly, focusing heavily on fundraising strategy development and implementation. This role is impactful because you'll serve as the primary spokesperson for the X and Y variation community while overseeing programs that directly support individuals with these genetic conditions.

💡 A Day in the Life

A typical day might involve morning virtual meetings with program managers to review community support initiatives, followed by afternoon work on grant proposals targeting medical research foundations. You'd likely spend time connecting with donor families, planning advocacy efforts with medical organizations, and overseeing the implementation of AXYS's strategic plan through remote team coordination.

🎯 Who AXYS Is Looking For

  • Has 3+ years of senior nonprofit management experience with demonstrated success in fundraising strategy implementation (not just participation)
  • Possesses hands-on budget management skills specifically in nonprofit contexts, including grant reporting and donor-restricted funds
  • Demonstrates knowledge of fundraising strategies unique to medical/health-focused nonprofits rather than general nonprofit fundraising
  • Has strong public speaking experience advocating for marginalized or medical communities, not just general communication skills

📝 Tips for Applying to AXYS

1

Quantify your nonprofit management experience with specific metrics: mention budget sizes managed, fundraising increases achieved, and program growth percentages

2

Highlight any experience with medical/health nonprofits or disability advocacy organizations, even if volunteer-based

3

Research AXYS's current programs (like their annual conference or research initiatives) and suggest specific improvements or expansions

4

Demonstrate understanding of X and Y chromosome variations by mentioning specific conditions AXYS serves (like 47,XXY or XYY syndrome)

5

Address how you would manage a 30-hour executive role specifically - describe your time management approach for part-time leadership

✉️ What to Emphasize in Your Cover Letter

['Your specific experience developing and implementing comprehensive fundraising strategies for nonprofits, with examples of successful campaigns', "How you've served as a spokesperson or advocate for a specific community, particularly in medical or disability contexts", 'Your approach to remote leadership and managing programs/projects in a distributed team environment', "Why you're personally drawn to AXYS's specific mission supporting X and Y chromosome variations rather than general nonprofit work"]

Generate Cover Letter →

🔍 Research Before Applying

To stand out, make sure you've researched:

  • AXYS's current programs and initiatives listed on their website, particularly their annual conference and research collaborations
  • The specific X and Y chromosome variations they serve (Klinefelter, Turner, Triple X, XYY, etc.) and current advocacy issues
  • Their current leadership team and board structure to understand organizational dynamics
  • Recent news or research about X/Y chromosome variations to demonstrate current knowledge of the field
Visit AXYS's Website →

💬 Prepare for These Interview Topics

Based on this role, you may be asked about:

1 How would you develop a fundraising strategy targeting both individual donors (affected families) and corporate partners in the medical/pharmaceutical space?
2 Describe your experience overseeing programs for a specific medical community and how you would adapt programs for X/Y variations
3 How would you serve as spokesperson to increase awareness of X/Y variations among medical professionals and the general public?
4 What's your approach to budget management for a small nonprofit with restricted funding sources?
5 How would you balance the 30-hour weekly commitment with the comprehensive responsibilities of an Executive Director?
Practice Interview Questions →

⚠️ Common Mistakes to Avoid

  • Applying with only corporate management experience without clear nonprofit translation - AXYS needs specific nonprofit expertise
  • Generic fundraising experience without medical/health nonprofit context - this community has unique donor motivations
  • Failing to demonstrate specific knowledge of X/Y chromosome variations or AXYS's current work in your application materials

📅 Application Timeline

This position is open until filled. However, we recommend applying as soon as possible as roles at mission-driven organizations tend to fill quickly.

Typical hiring timeline:

1

Application Review

1-2 weeks

2

Initial Screening

Phone call or written assessment

3

Interviews

1-2 rounds, usually virtual

Offer

Congratulations!

Ready to Apply?

Good luck with your application to AXYS!