Impact Careers Full-time

Director, Protein & Cell Sciences

Flagship Pioneering

Posted

Feb 07, 2026

Location

USA

Type

Full-time

Compensation

$183000 - $231000

Mission

What you will drive

Core responsibilities:

  • Lead a focused team responsible for high-throughput production and characterization of antibodies and related proteins, and for cell culture, engineering, and scale-up of antibody/protein production up to the multi-gram scale to support research activities
  • Deliver high-quality antibodies and protein reagents for multiple simultaneous biologics discovery programs, enabling discovery platform optimization
  • Manage a team of direct and indirect reports, and coordinate both in-house and outsourced protein expression, purification, and characterization activities
  • Establish and maintain a Protein & Cell Sciences function that maximizes the potential for Metaphore's platform to deliver transformative therapeutics to patients

Impact

The difference you'll make

This role enables the delivery of transformative therapeutics to patients through generative AI drug design focused on creating a new class of functional antibodies, contributing to the advancement of the internal and partnered portfolio and developing novel platforms and techniques.

Profile

What makes you a great fit

Required qualifications:

  • PhD in Protein Biochemistry, Molecular and Cell Biology, Structural Biology, or a related discipline, or non-PhD with appropriate skills and experience
  • 10+ years of experience in biologics drug discovery and development
  • Deep knowledge of antibody expression, purification, and characterization workflows, including the implementation of automation solutions to enable high-throughput protein production
  • Experience managing biologics CROs to expand protein production/characterization capabilities and capacity
  • Strong interpersonal and communication skills, with an established track record of leading and developing people and teams in a fast-paced, entrepreneurial biotech environment

Benefits

What's in it for you

Compensation and benefits:

  • Salary range: $183,000 - $231,000
  • Healthcare coverage
  • Annual incentive program
  • Retirement benefits
  • Broad range of other benefits