Director, Protein & Cell Sciences
Flagship Pioneering
Posted
Feb 07, 2026
Location
USA
Type
Full-time
Compensation
$183000 - $231000
Mission
What you will drive
Core responsibilities:
- Lead a focused team responsible for high-throughput production and characterization of antibodies and related proteins, and for cell culture, engineering, and scale-up of antibody/protein production up to the multi-gram scale to support research activities
- Deliver high-quality antibodies and protein reagents for multiple simultaneous biologics discovery programs, enabling discovery platform optimization
- Manage a team of direct and indirect reports, and coordinate both in-house and outsourced protein expression, purification, and characterization activities
- Establish and maintain a Protein & Cell Sciences function that maximizes the potential for Metaphore's platform to deliver transformative therapeutics to patients
Impact
The difference you'll make
This role enables the delivery of transformative therapeutics to patients through generative AI drug design focused on creating a new class of functional antibodies, contributing to the advancement of the internal and partnered portfolio and developing novel platforms and techniques.
Profile
What makes you a great fit
Required qualifications:
- PhD in Protein Biochemistry, Molecular and Cell Biology, Structural Biology, or a related discipline, or non-PhD with appropriate skills and experience
- 10+ years of experience in biologics drug discovery and development
- Deep knowledge of antibody expression, purification, and characterization workflows, including the implementation of automation solutions to enable high-throughput protein production
- Experience managing biologics CROs to expand protein production/characterization capabilities and capacity
- Strong interpersonal and communication skills, with an established track record of leading and developing people and teams in a fast-paced, entrepreneurial biotech environment
Benefits
What's in it for you
Compensation and benefits:
- Salary range: $183,000 - $231,000
- Healthcare coverage
- Annual incentive program
- Retirement benefits
- Broad range of other benefits